The Best Multivitamins for Women Over 45: Our Picks to Stay Healthy and Vibrant

These supplements have what you need.


There’s a lot for women over 45 to consider when choosing a daily multivitamin. As we age, our bodies need more of certain vitamins and minerals and less of others. But with so many different supplements out there, where do you start? 

What do women over 45 need in a multivitamin?

There are a few specific things you should be on the lookout for when shopping for the best multivitamins for women over 45. Supplements geared toward mature women are formulated much differently than your average daily multivitamin, and with good reason! As we get older, we require a higher daily intake of calcium, magnesium, and vitamin D3 (all of which you can also buy as standalone supplements). 

Thanks to a natural decrease in bone density, our bones become more delicate as we age. Adding multivitamins rich in calcium and vitamin D3 to your diet can help strengthen them, reducing your chances of fractures, breaks, or developing osteoporosis.  

Be Aware of Your Iron Intake

At the same time that our bodies begin to require an extra boost in the aforementioned supplements, we start to need less of other minerals, such as iron. Normally, women’s daily multivitamins contain a high dosage of iron to make up for the amount lost each month during menstruation. However, as we reach menopause, it’s recommended that we lower our iron intake. That extra dose of iron is not only no longer needed, it can become potentially harmful when taken in supplemental form. 

Healthy Gut, Healthy Life

The true key to optimal health in your 40s and beyond is a healthy digestive system, so picking up a multivitamin that includes a probiotic is the way to go. Why are probiotics so important? Studies show that three of the most common health issues that can develop in our later years include malnutrition, constipation, and a weakened immune system — all things that can be improved with daily intake of a probiotic.

This makes a great deal of sense, considering the gut is where our nutrients are processed, as well as the heart of our immune system. As nutritionist Jonny Bowden, author of The 150 Healthiest Foods on Earth, said: “If your gut isn’t healthy, your body can’t absorb nutrients, so it doesn’t matter what supplements you take.”

Best Supplements for Women Over 45

Taking a daily multivitamin with the correct ingredients can not only improve your day-to-day functioning, but can add years to your life. Want to know where you can get some of the best multivitamins around? Keep scrolling for FIRST for Women’s picks for the best multivitamins for women over 45!

See more of our best product recommendations.

We write about products we think our readers will like. If you buy them, we get a small share of the revenue from the supplier.

Nature’s Way Alive! Once Daily

best multivitamins for women over 45

Where to buy: $13.20, Amazon

This ultra-potent, food-based multivitamin from Nature’s Way is one of the best supplements on the market. Formulated with 26 fruits and vegetables, 22 vitamins and minerals, 14 green foods, 12 organic mushrooms, and 12 digestive enzymes, to say this pick is “well-rounded” is an understatement. This multivitamin is also a great source of Vitamin D3, meaning it’s a great choice for women over 50. 

Rainbow Light 50+ Mini-Tablet

best multivitamins for women over 45

Where to buy: From $32.95, Amazon

One of the latest companies to hit it big in the vitamin world is Rainbow Light, thanks to its incredible range of multivitamins. This one caters to those over 50 and provides everything mature bodies need to thrive daily. With a vitality blend that’s filled with vegetable concentrates for natural energy, a probiotic blend to promote healthy digestion, and Vitamin D3 for calcium absorption, this easy-to-swallow pill is a great addition to anyone’s morning routine.

Vitanica Senior Symmetry

best multivitamins for women over 45

Where to buy: $44.94, Amazon

Hypoallergenic and free of preservatives, this multivitamin was specifically made with older women in mind. The Vitanica Senior Symmetry Multivitamin was formulated with calcium and D2 for bone health, Co-Q-10 for memory, and plant-based digestive enzymes for smoother digestion, plus additional nutrients selected to aid in your day-to-day life.

MegaFood Multi

best multivitamins for women over 45

Where to buy: From $25.89, Amazon

Some people shy away from taking supplements out of fear of ingesting unidentified ingredients, but with this multivitamin from MegaFood, you can rest assured you’re getting one of the most natural supplements around. Every vitamin and mineral found within is sourced from fresh, whole foods to deliver “cautious dietary supplements” and “authentic nutrition” while also being tailored to meet the changing needs of women over 50.

New Chapter Every Woman’s One Daily 40+

best multivitamins for women over 45

Where to buy: $18.45, Amazon

Another top pick as far as natural supplements go comes in the form of New Chapter, which boasts high-grade probiotics and whole foods formulation. With multiple benefits for women over 40, this non-GMO and gluten-free multivitamin is great for stress support, bone support, immune support, energy support, and superfood implementation. This option is also suitable for those with food sensitivities, since it’s gentle enough to take on an empty stomach.

Multifactors by Natural Factors

best multivitamins for women over 45

Where to buy: $20.27, Amazon

Containing more than 35 essential nutrients, enzymes, antioxidants, and herbal extracts, this certified organic, non-GMO multivitamin is a great choice for women over 50. Need more convincing? This easy-to-swallow supplement is also sustainably-made, so you can feel good about buying it.

One A Day 50+ Healthy Advantage

best multivitamins for women over 45

Where to buy: $22.73, Amazon

A classic in the world of multivitamins, you’re probably no stranger to One A Day’s 50+ Healthy Advantage.  Packed with all the ingredients mature women need to maintain optimal health, including ginkgo biloba for memory, vitamin D3 for strong bones, and other key nutrients and antioxidants to ensure joint, heart, breast and eye health, this is one of the most well-rounded multivitamins on the list.

21st Century Sentry Senior Women 50 Plus+

best multivitamins for women over 45

Where to buy: $7.99, Amazon

With excellent daily amounts of vitamin D3, calcium, zinc, lutein, and folic acid, this super-affordable multivitamin is the perfect option if you’re looking for a budget-friendly find. Sentry Senior from 21st Century Vitamins boasts the “highest quality ingredients produced to strict standards of quality for your good health,” and reviewers seem to agree. Amazon buyer Grandma Judy called these multivitamins “an excellent product.” 

This article originally appeared on our sister site, Woman’s World.

Keep scrolling, there's more!
Use left and right arrow keys to navigate between menu items. Use right arrow key to move into submenus. Use escape to exit the menu. Use up and down arrow keys to explore. Use left arrow key to move back to the parent list.